Article
Production of autoantibodies against citrullinated antigens/peptides by human B cells.
Journal of immunology (Baltimore, Md. : 1950) - 1 Apr 2012
Bellatin Maria F, Han Mei, Fallena Margarita, Fan Lin, Xia Donglan, Olsen Nancy, Branch Valerie, Karp David, Stastny Peter
Abstract excerpt
Autoantibodies against citrullinated protein Ags (ACPA) are associated with the development of rheumatoid arthritis (RA). This immune response against citrullinated protein Ags, which is thought to be facilitated by certain MHC HLA-DR alleles, is highly specific for this disease and has been spec...
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