Article
Role of ERRF, a novel ER-related nuclear factor, in the growth control of ER-positive human breast cancer cells.
The American journal of pathology - 1 Mar 2012
Su Dan, Fu Xiaoying, Fan Songqing, Wu Xiao, Wang Xin-Xin, Fu Liya, Dong Xue-Yuan, Ni Jianping Jenny, Fu Li, Zhu Zhengmao, Dong Jin-Tang
Abstract excerpt
Whereas estrogen-estrogen receptor α (ER) signaling plays an important role in breast cancer growth, it is also necessary for the differentiation of normal breast epithelial cells. How this functional conversion occurs, however, remains unknown. Based on a genome-wide sequencing study that identified mutations in several breast cancer genes, we examined some of the genes for mutations, expression levels, and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
