Article
[Studying on the prevalence and mutation pattern of N348I which related to the resistance of HIV-1].
Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi - 1 Sept 2011
Li Han-ping, Han Yang, Zhu Xin-peng, Lu Xin-li, Guo Wei, Liu Yong-jian, Bao Zuo-yi, Li Lin, Zhuang Dao-min, Liu Si-yang, Li Jing-yun
Abstract excerpt
OBJECTIVE: To elucidate the prevalence and the mutation pattern of N348I that related to the resistance seen in the AIDS patients, in China. METHODS: Partial pol gene of HIV-1 comprising of full protease (PR) and reverse transcriptase (RT) was obtained from plasma samples of therapy-failure individuals (n = 614) and therapy-naive individuals (n = 619) by using reverse transcription polymerase chain reaction...
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