Article
[Evolution of HIV-1 drug resistance in patients failing combination antiretroviral therapy].
Zhonghua yi xue za zhi - 9 Mar 2010
Wang Hui, Zhang Hong-mei, Jiang Qiang, Peng Qiao-li, Tan Yan, Li Tai-sheng, Zhou Bo-ping
Abstract excerpt
OBJECTIVE: This study aimed to evolution of genotypic drug resistance prevalence in treatment-failing patients in Shenzhen. METHODS: Peripheral venous blood samples were collected from 41 AIDS patients whom failing combination antiretroviral therapy, and were amplified by nested PCR; then the amplified fragments were sequenced and analyzed. RESULTS: Partial pol sequences of 38 samples were successfully amplified,...
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