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Article

Familial Mediterranean fever-associated mutation pyrin E148Q as a potential risk factor for multiple sclerosis.

Multiple sclerosis (Houndmills, Basingstoke, England) - 1 Sept 2012

Kümpfel T, Gerdes L-A, Wacker T, Blaschek A, Havla J, Krumbholz M, Pöllmann W, Feneberg W, Hohlfeld R, Lohse P

Abstract excerpt

BACKGROUND: Familial Mediterranean fever (FMF) is an inherited autoinflammatory disease caused by mutations in the MEFV gene and characterized by recurrent febrile polyserositis. A possible association of FMF and multiple sclerosis (MS) has been suggested in cohorts from Turkey and Israel. OBJECTIVE: The objective of this study was to investigate the prevalence of MEFV mutations in subjects with MS and in...

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Identifiers

PMID: 22337722
DOI: 10.1177/1352458512437813

Genes

MEFV

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