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Article

The genetic basis of autosomal dominant familial Mediterranean fever.

QJM : monthly journal of the Association of Physicians - 1 Apr 2000

Booth D R, Gillmore J D, Lachmann H J, Booth S E, Bybee A, Soytürk M, Akar S, Pepys M B, Tunca M, Hawkins P N

Abstract excerpt

Familial Mediterranean fever (FMF) is classically an autosomal recessive periodic inflammatory disease occurring in Mediterranean and Middle Eastern populations. It is caused by mutations affecting both alleles of MEFV, a gene that encodes pyrin (marenostrin), an uncharacterized neutrophil protei...

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Source

Identifiers

PMID: 10787449
DOI: 10.1093/qjmed/93.4.217

Genes

MEFV

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-10787449-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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