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Transcriptomic and Epigenetic Preservation of Genetic Sex Identity in Estrogen-feminized Male Chicken Embryonic Gonads

10 Nov 2020

Abstract excerpt

Whereas in ovo exposure of genetically male (ZZ) chicken embryos to exogenous estrogens temporarily feminizes gonads at the time of hatching, the morphologically ovarian ZZ-gonads (FemZZs for feminized ZZ gonads) are masculinized back to testes within 1 year. To identify the feminization-resistant "memory" of genetic male sex, FemZZs showing varying degrees of feminization were subjected to transcriptomic, DNA...

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Animal Genetics and Reproduction
Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Sperm and Testicular Function

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PMID: 33170207
DOI: 10.1210/endocr/bqaa208

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