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Article

DNA hypomethylation at ALOX12 is associated with persistent wheezing in childhood.

American journal of respiratory and critical care medicine - 1 May 2012

Morales Eva, Bustamante Mariona, Vilahur Nadia, Escaramis Georgia, Montfort Magda, de Cid Rafael, Garcia-Esteban Raquel, Torrent Maties, Estivill Xavier, Grimalt Joan O, Sunyer Jordi

Abstract excerpt

RATIONALE: Epigenetic changes may play a role in the occurrence of asthma-related phenotypes. OBJECTIVES: To identify epigenetic marks in terms of DNA methylation of asthma-related phenotypes in childhood, and to assess the effect of prenatal exposures and genetic variation on these epigenetic marks. METHODS: Data came from two cohorts embedded in the Infancia y Medio Ambiente (INMA) PROJECT: Menorca (n = 122)...

Read the complete abstract on PubMed

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Share to Arachidonate 12-Lipoxygenase
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Methylation

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Share to Prenatal Exposure Delayed Effects

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Source

Identifiers

PMID: 22323304
DOI: 10.1164/rccm.201105-0870OC

Genes

ALOX12

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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