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Article

MicroRNA-1322 regulates ECRG2 allele specifically and acts as a potential biomarker in patients with esophageal squamous cell carcinoma.

Molecular carcinogenesis - 1 Aug 2013

Zhang Tengfei, Zhao Dan, Wang Qiming, Yu Xiying, Cui Yaling, Guo Liping, Lu Shih Hsin

Abstract excerpt

A short tandem repeat (STR) polymorphism in the 3'UTR region of esophageal cancer-related gene 2 (ECRG2, also known as SPINK7) has been widely reported to be associated with the incidence and the prognosis of esophageal squamous cell carcinoma (ESCC). This study explores how the microRNA binding to the STR region affects ECRG2 expression in ESCC. Dual-luciferase reporter assays were used to verify the effects of...

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Source

Identifiers

PMID: 22315007
DOI: 10.1002/mc.21880

Genes

SPINK7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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