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Article

Polymorphisms of LTA, LGALS2, and PSMA6 genes and coronary atherosclerosis: a pathological study of 1503 consecutive autopsy cases.

Atherosclerosis - 1 Apr 2012

Ikeda Shinobu, Tanaka Noriko, Arai Tomio, Chida Kouji, Muramatsu Masaaki, Sawabe Motoji

Abstract excerpt

OBJECTIVE: Recent genome-wide association studies have identified polymorphisms of lymphotoxin-α (LTA), galectin-2 (LGALS2), and proteasome subunit a type 6 (PSMA6) genes as genetic risk factors for myocardial infarction (MI). However, their effects on coronary atherosclerosis, an intermediate phenotype of MI, remain largely unknown. METHODS: We investigated the correlation between polymorphisms of the LTA,...

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Source

Identifiers

PMID: 22310064
DOI: 10.1016/j.atherosclerosis.2012.01.003

Genes

LGALS2
LTA
PSMA6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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Polymorphisms of LTA, LGALS2, and PSMA6 genes and coronary atherosclerosis: a pathological study of 1503 consecutive autopsy cases.PMID 22310064Read ↗

Genome-wide association study to identify SNPs conferring risk of myocardial infarction and their functional analyses.Semantic proximity Read ↗

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Lymphotoxin-alpha gene and risk of myocardial infarction in 6,928 cases and 2,712 controls in the ISIS case-control study.Semantic proximity Read ↗

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Polymorphisms of the LTA gene may contribute to the risk of myocardial infarction: a meta-analysis.Semantic proximity Read ↗

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Genome-wide association study to identify single-nucleotide polymorphisms conferring risk of myocardial infarction.Semantic proximity Read ↗

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