Article
[Genetic background of acute coronary syndrome].
Nihon rinsho. Japanese journal of clinical medicine - 1 Apr 2010
Ozaki Kouichi
Abstract excerpt
Development of acute coronary syndrome(ACS) including angina pectoris(AP) and myocardial infarction(MI) depends on complex interactions of environmental and genetic factors. In 2000, we started a genome wide association study(GWAS) for MI using nearly 100,000 gene-based single nucleotide polymorphisms(SNP), and identified lymphotoxin a (LTA) conferring risk of MI in Japanese population. This is the first study...
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