Article
[Obtaining and characteristic of Streptomyces globisporus 1912 mutants with high biosynthesis of landomycin e].
Mikrobiolohichnyi zhurnal (Kiev, Ukraine : 1993) - 1 Jan 2000
Lavrinchuk B Ia, Kotenko K A, Golembiovs'ka S L, Matseliukh B P
Abstract excerpt
Eight highly productive UV-induced mutants of Streptomyces globisporus 1912 with high biosynthesis of landomycin E were isolated, their isolation frequency being 2 x 10(-3). Mutants 1-1, 1-4-1, 1-1y, 1-2y, 4-1, 1-2 produced 175-187.5 mg of landomycine E and 1-1b, 4-1-1 and 1-3--80-100 mg per 1 liter of soybean agar after 48 hours of cultivation The mutant 4-1-1 had the highest antibiotic activity and middle level...
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