Article
Dispersible amyloid β-protein oligomers, protofibrils, and fibrils represent diffusible but not soluble aggregates: their role in neurodegeneration in amyloid precursor protein (APP) transgenic mice.
Neurobiology of aging - 1 Nov 2012
Rijal Upadhaya Ajeet, Capetillo-Zarate Estibaliz, Kosterin Irina, Abramowski Dorothee, Kumar Sathish, Yamaguchi Haruyasu, Walter Jochen, Fändrich Marcus, Staufenbiel Matthias, Thal Dietmar Rudolf
Abstract excerpt
Soluble amyloid β-protein (Aβ) aggregates have been identified in the Alzheimer's disease (AD) brain. Dispersed Aβ aggregates in the brain parenchyma are different from soluble, membrane-associated and plaque-associated solid aggregates. They are in mixture with the extra- or intracellular fluid...
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