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Article

Disulfide linkages mediating nucleocapsid protein dimerization are not required for porcine arterivirus infectivity.

Journal of virology - 1 Apr 2012

Zhang Rong, Chen Chunyan, Sun Zhi, Tan Feifei, Zhuang Jinshan, Tian Debin, Tong Guangzhi, Yuan Shishan

Abstract excerpt

The nucleocapsid (N) proteins of the North American (type II) and European (type I) genotypes of porcine reproductive and respiratory syndrome virus (PRRSV) share only approximately 60% genetic identity, and the functionality of N in both genotypes, especially its role in virion assembly, is still poorly understood. In this study, we demonstrated that the ORF7 3' untranslated region or ORF7 of type I is...

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Identifiers

PMID: 22301142
DOI: 10.1128/JVI.06709-11
PMCID: PMC3318635

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