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Article

An unusual phenotypic and genotypic expression in F2 generation following one stage zidovudine exposure during pregnancy and lactation- an experiment in mice.

The Journal of toxicological sciences - 1 Feb 2012

Rajlakshmi Chongtham, Roy Jagat Kumar, Rai Amit Kumar, Bhattacharyya Asima, Pandey Bajarang Lal

Abstract excerpt

Zidovudine (3'-Azido-2', 3'-dideoxythymidine, AZT, ZDV) is routinely used as one of the component of antiretroviral therapy to prevent transmission of the HIV infection from mother to child. The drug, when given during pregnancy can give rise to myriad toxicities as reported in previous studies on human, animal and in-vitro experiments. The present study was an attempt to explore the Zidovudine teratogenesis in...

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Identifiers

PMID: 22293411
DOI: 10.2131/jts.37.51

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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