Article
Combining evidence of selection with association analysis increases power to detect regions influencing complex traits in dairy cattle.
BMC genomics - 30 Jan 2012
Schwarzenbacher Hermann, Dolezal Marlies, Flisikowski Krzysztof, Seefried Franz, Wurmser Christine, Schlötterer Christian, Fries Ruedi
Abstract excerpt
BACKGROUND: Hitchhiking mapping and association studies are two popular approaches to map genotypes to phenotypes. In this study we combine both approaches to complement their specific strengths and weaknesses, resulting in a method with higher statistical power and fewer false positive signals....
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