Article
Combining evidence of selection with association analysis increases power to detect regions influencing complex traits in dairy cattle.
BMC genomics - 30 Jan 2012
Schwarzenbacher Hermann, Dolezal Marlies, Flisikowski Krzysztof, Seefried Franz, Wurmser Christine, Schlötterer Christian, Fries Ruedi
Abstract excerpt
BACKGROUND: Hitchhiking mapping and association studies are two popular approaches to map genotypes to phenotypes. In this study we combine both approaches to complement their specific strengths and weaknesses, resulting in a method with higher statistical power and fewer false positive signals. We applied our approach to dairy cattle as they underwent extremely successful selection for milk production traits and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.