Article
Lack of significant influence for FcγRIIa-RH131 or hemoglobin AA/AS polymorphisms on immunity and susceptibility to uncomplicated malaria and existence of marked linkage between the two polymorphisms in Daraweesh.
Microbes and infection - 1 Jun 2012
Giha Hayder A, Nasr Amre, Iriemenam Nnaemeka C, Troye-Blomberg Marita, Berzins Klavs, ElGhazali Gehad
Abstract excerpt
Malaria signature on human genome is marked by several gene polymorphisms. HemoglobinAS (HbAS) is known to protect against severe malaria, but barely proved to protect against uncomplicated malaria (UM). Similarly, the influence of FcγRIIa-RH131 polymorphism on malaria is controversial. Polymorphisms in both genes were examined and levels of IgG subclasses against four malaria antigens were measured for 250...
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