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Article

Identification of candidate genes carrying polymorphisms associated with the risk of colorectal cancer by analyzing the colorectal mutome and microRNAome.

Cancer - 1 Oct 2012

Landi Debora, Gemignani Federica, Pardini Barbara, Naccarati Alessio, Garritano Sonia, Vodicka Pavel, Vodickova Ludmila, Canzian Federico, Novotny Jan, Barale Roberto, Landi Stefano

Abstract excerpt

BACKGROUND: The presence of single-nucleotide polymorphisms (SNPs) within the 3'-untranslated regions of genes could affect the binding between a microRNA (miRNA) and its target, with consequences on gene expression regulation. Considering the important role of miRNAs in carcinogenesis, it is hypothesized here that these SNPs could also affect the individual risk of colorectal cancer (CRC). METHODS: To test this...

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PMID: 22282400
DOI: 10.1002/cncr.27435

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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