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Article

Mutant mice derived by ICSI of evaporatively dried spermatozoa exhibit expected phenotype.

Reproduction (Cambridge, England) - 1 Apr 2012

Li Ming-Wen, Baridon Brian, Trainor Amanda, Djan Esi, Koehne Amanda, Griffey Stephen M, Biggers John D, Toner Mehmet, Lloyd K C Kent

Abstract excerpt

Apolipoprotein E (Apoe)-deficient knockout mice were used to test the hypothesis that mutant mice preserved as evaporatively dried (ED) spermatozoa, stored at -80 °C for 6 months, and then recovered by ICSI will exhibit the same phenotype as before preservation. The birth rate of mice recovered b...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22274886
DOI: 10.1530/REP-12-0005
PMCID: PMC3738174

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22274886-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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