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Article

Host genetics and environmental factors regulate ecological succession of the mouse colon tissue-associated microbiota.

PloS one - 1 Jan 2012

Smith Philip, Siddharth Jay, Pearson Ruth, Holway Nicholas, Shaxted Mark, Butler Matt, Clark Natalie, Jamontt Joanna, Watson Robert P, Sanmugalingam Devika, Parkinson Scott J

Abstract excerpt

BACKGROUND: The integration of host genetics, environmental triggers and the microbiota is a recognised factor in the pathogenesis of barrier function diseases such as IBD. In order to determine how these factors interact to regulate the host immune response and ecological succession of the colon tissue-associated microbiota, we investigated the temporal interaction between the microbiota and the host following...

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Identifiers

PMID: 22272321
DOI: 10.1371/journal.pone.0030273
PMCID: PMC3260280

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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