Article
Proteins involved in extracellular matrix dynamics are associated with respiratory syncytial virus disease severity.
The European respiratory journal - 1 Jun 2012
Schuurhof Annemieke, Bont Louis, Hodemaekers Hennie M, de Klerk Arja, de Groot Hanneke, Hofland Regina W, van de Pol Alma C, Kimpen Jan L L, Janssen Riny
Abstract excerpt
Severity of respiratory syncytial virus (RSV) infection ranges widely. To what extent the local immune response is involved in RSV disease pathogenesis and which markers of this response are critical in determining disease severity is still a matter of debate. The local immune response was studied in nasopharyngeal aspirates (NPAs) during RSV infection. 47 potential markers of disease severity were analysed in a...
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