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Article

Molecular damage in cancer: an argument for mTOR-driven aging

31 Dec 2011

Abstract excerpt

Despite common belief, accumulation of molecular damage does not play a key role in aging. Still, cancer (an age-related disease) is initiated by molecular damage. Cancer and aging share a lot in common including the activation of the TOR pathway. But the role of molecular damage distinguishes cancer and aging. Furthermore, an analysis of the role of both damage and aging in cancer argues against "a decline,...

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PMID: 22246147
DOI: 10.18632/aging.100422

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