Article
Gastrointestinal tumors in transplantation: Two case reports and review of literature.
World journal of gastroenterology - 14 Sept 2022
Stammler Romain, Anglicheau Dany, Landi Bruno, Meatchi Tchao, Ragot Emilia, Thervet Eric, Lazareth Hélène
Abstract excerpt
BACKGROUND: Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract. As most of them harbor a KIT mutation (75%), selective kinase inhibitors are the therapeutic option and show a sustained objective response among patients with metastatic or unresectable GISTs. A well-known higher risk of neoplasm has been described among renal transplant recipients (RTRs)....
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