Article
KRAS status in patients with colorectal cancer peritoneal carcinomatosis and its impact on outcome.
American journal of clinical oncology - 1 Oct 2010
Gillern Suzanne M, Chua Terence C, Stojadinovic Alexander, Esquivel Jesus
Abstract excerpt
BACKGROUND: KRAS mutated colorectal cancers (CRC) are reported to be associated with a poor response to anti-EGFR monoclonal antibody therapy and poor prognosis. We studied the rates of KRAS mutated tumors in patients with peritoneal carcinomatosis from CRC and investigated the association of KRAS status with specific clinicopathologic factors. METHODS: A retrospective observational study of tumor specimens from...
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