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Global gene analysis of oocytes from early stages in human folliculogenesis shows high expression of novel genes in reproduction

10 Jan 2012

Abstract excerpt

The pool of primordial follicles in humans is laid down during embryonic development and follicles can remain dormant for prolonged intervals, often decades, until individual follicles resume growth. The mechanisms that induce growth and maturation of primordial follicles are poorly understood but follicles once activated either continue growth or undergo atresia. We have isolated pure populations of oocytes from...

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PMID: 22238370
DOI: 10.1093/molehr/gar083

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