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Article

Impact of a baseline polymorphism on the emergence of resistance to the hepatitis C virus nonstructural protein 5A replication complex inhibitor, BMS-790052.

Hepatology (Baltimore, Md.) - 1 Jun 2012

Sun Jin-Hua, O'Boyle Ii Donald R, Zhang Yan, Wang Chunfu, Nower Peter, Valera Lourdes, Roberts Susan, Nettles Richard E, Fridell Robert A, Gao Min

Abstract excerpt

UNLABELLED: The influence of naturally occurring polymorphisms on the potency of the HCV nonstructural protein 5A (NS5A) replication complex inhibitor, BMS-790052, was investigated by evaluating hybrid replicons in which the entire NS5A coding region of genotype (GT) la and 1b laboratory (lab) strains (H77c and Con1) were replaced with the corresponding regions of specimens collected from 10 GT-1a- and 6...

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PMID: 22234905
DOI: 10.1002/hep.25581

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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