Article
In vitro activity of BMS-790052 on hepatitis C virus genotype 4 NS5A.
Antimicrobial agents and chemotherapy - 1 Mar 2012
Wang Chunfu, Jia Lingling, Huang Haichang, Qiu Dike, Valera Lourdes, Huang Xin, Sun Jin-Hua, Nower Peter T, O'Boyle Donald R, Gao Min, Fridell Robert A
Abstract excerpt
The antiviral profile of BMS-790052, a potent hepatitis C virus (HCV) replication complex inhibitor targeting nonstructural protein NS5A, is well characterized for HCV genotype-1. Here, we report that BMS-790052 inhibits hybrid replicons containing HCV genotype-4 NS5A genes with 50% effective con...
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