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Article

Evidence for epistatic gene interactions between growth factor genes in stroke outcome.

European journal of neurology - 1 Aug 2012

Manso H, Krug T, Sobral J, Albergaria I, Gaspar G, Ferro J M, Oliveira S A, Vicente A M

Abstract excerpt

BACKGROUND AND PURPOSE: Growth factors are thought to modulate neurological function in stroke recovery through effects in angiogenesis, neurogenesis, and neuroprotection. METHODS: We tested the association of variants in the brain-derived neurotrophic factor (BDNF), fibroblast growth factor 2 (FGF2) and vascular endothelial growth factor A (VEGFA) genes, and epistatic interactions between them, with functional...

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Topics

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Share to Brain-Derived Neurotrophic Factor
Share to Epistasis, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fibroblast Growth Factor 2

Share to Polymorphism, Single Nucleotide

Share to Recovery of Function

Share to Stroke

Share to Treatment Outcome

Share to Vascular Endothelial Growth Factor A

Source

Identifiers

PMID: 22233184
DOI: 10.1111/j.1468-1331.2011.03625.x

Genes

FGF2
BDNF
VEGFA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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