Long-Term Therapy with Growth Hormone: Bringing Sagacity to SAGHE

Abstract excerpt

GH is an anterior pituitary protein secreted by somatotrophs under complex neural, hormonal, and metabolic control (1). So named because of its remarkable effects on growth when in excess (gigantism-acromegaly) or deficient (dwarfism), the hormone also has profound metabolic actions, antagonizing insulin action, promoting lipolysis in fat, and augmenting protein synthesis. These actions facilitate the integration...

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