Article
Correlation of the vesicular acetylcholine transporter densities in the striata to the clinical abilities of women with Rett syndrome.
Synapse (New York, N.Y.) - 1 Jun 2012
Brašić James Robert, Bibat Genila, Kumar Anil, Zhou Yun, Hilton John, Yablonski Marybeth E, Dogan Ahmet Semih, Guevara Maria Rita, Stephane Massoud, Johnston Michael, Wong Dean Foster, Naidu Sakkubai
Abstract excerpt
Rett syndrome (RTT) is a neurodevelopmental disability characterized by mutations in the X-linked methyl-CpG-binding protein 2 located at the Xq28 region. The severity is modified in part by X chromosomal inactivation resulting in wide clinical variability. We hypothesized that the ability to perform the activities of daily living (ADL) is correlated with the density of vesicular acetylcholine transporters in the...
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