Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic testing in familial and young-onset Alzheimer's disease: mutation spectrum in a Serbian cohort.

Neurobiology of aging - 1 Jul 2012

Dobricic Valerija, Stefanova Elka, Jankovic Milena, Gurunlian Nicole, Novakovic Ivana, Hardy John, Kostic Vladimir, Guerreiro Rita

Abstract excerpt

Alzheimer's disease (AD) is the most common form of dementia. To date, more than 200 mutations in three genes have been identified as cause of early-onset autosomal dominant inherited AD. The aim of this study was to characterize the mutation spectrum and describe genotype-phenotype correlations in Serbian patients with positive family history of AD or/and early-onset AD. We performed a genetic screening for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age of Onset
Share to Alzheimer Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Amyloid beta-Protein Precursor

Share to Cohort Studies

Share to Genetic Testing

Share to Presenilin-1

Share to Presenilin-2

Share to Serbia

Source

Identifiers

PMID: 22221884
DOI: 10.1016/j.neurobiolaging.2011.12.007

Genes

PSEN1
APP
PSEN2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic testing in familial and young-onset Alzheimer's disease: mutation spectrum in a Serbian cohort.PMID 22221884Read ↗

APP, PSEN1, and PSEN2 mutations in early-onset Alzheimer disease: A genetic screening study of familial and sporadic cases.Semantic proximity Read ↗

Genetic analyses of early-onset Alzheimer’s disease using next generation sequencingSemantic proximity Read ↗

APP, PSEN1, and PSEN2 Mutations in Asian Patients with Early-Onset Alzheimer DiseaseSemantic proximity Read ↗

Mutations, associated with early-onset Alzheimer's disease, discovered in Asian countries.Semantic proximity Read ↗

Mutation analysis of disease causing genes in patients with early onset or familial forms of Alzheimer's disease and frontotemporal dementia.Semantic proximity Read ↗

Identification of PSEN1 and PSEN2 gene mutations and variants in Turkish dementia patients.Semantic proximity Read ↗

Genetic screening of Alzheimer's disease genes in Iberian and African samples yields novel mutations in presenilins and APP.Semantic proximity Read ↗

Molecular genetics of Alzheimer's disease: an update.Semantic proximity Read ↗

Screening for Genetic Mutations Associated with Early-Onset Alzheimer's Disease in Han Chinese.Semantic proximity Read ↗

Dementia-related genetic variants in an Italian population of early-onset Alzheimer’s diseaseSemantic proximity Read ↗

Genetics of dementia: update and guidelines for the clinician.Semantic proximity Read ↗

Early-onset familial Alzheimer's disease (EOFAD).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.