Article
Review of experimental animal models of biliary acute pancreatitis and recent advances in basic research.
HPB : the official journal of the International Hepato Pancreato Biliary Association - 1 Feb 2012
Wan Mei H, Huang Wei, Latawiec Diane, Jiang Kun, Booth David M, Elliott Victoria, Mukherjee Rajarshi, Xia Qing
Abstract excerpt
Acute pancreatitis (AP) is a formidable disease, which, in severe forms, causes significant mortality. Biliary AP, or gallstone obstruction-associated AP, accounts for 30-50% of all clinical cases of AP. In biliary AP, pancreatic acinar cell (PAC) death (the initiating event in the disease) is believed to occur as acinar cells make contact with bile salts when bile refluxes into the pancreatic duct. Recent...
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