Article
Diversity in parasitic nematode genomes: the microRNAs of Brugia pahangi and Haemonchus contortus are largely novel.
BMC genomics - 4 Jan 2012
Winter Alan D, Weir William, Hunt Martin, Berriman Matthew, Gilleard John S, Devaney Eileen, Britton Collette
Abstract excerpt
BACKGROUND: MicroRNAs (miRNAs) play key roles in regulating post-transcriptional gene expression and are essential for development in the free-living nematode Caenorhabditis elegans and in higher organisms. Whether microRNAs are involved in regulating developmental programs of parasitic nematodes is currently unknown. Here we describe the the miRNA repertoire of two important parasitic nematodes as an essential...
Topics
- Animals
- Brugia pahangi
- Caenorhabditis elegans
- Cluster Analysis
- Computational Biology
- Genes, Helminth
- Genetic Variation
- Genome, Helminth
- Haemonchus
- Larva
- MicroRNAs