Transferable Multidrug Resistance Plasmid Carrying cfr Associated with tet (L), ant(4 ′ )-Ia , and dfrK Genes from a Clinical Methicillin-Resistant Staphylococcus aureus ST125 Strain

Abstract excerpt

A multidrug resistance (MDR) conjugative plasmid of ca. 50 kb (designated pERGB) was detected in a linezolid and methicillin-resistant Staphylococcus aureus strain with sequence type 125 (ST125-MRSA-IVc). This strain was detected in two patients with chronic obstructive pulmonary disease, previously treated with multiple antimicrobials, including linezolid. pERGB was transferable by conjugation and carried the...

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