Article
Detailed interrogation of trypanosome cell biology via differential organelle staining and automated image analysis
3 Jan 2012
Abstract excerpt
BACKGROUND: Many trypanosomatid protozoa are important human or animal pathogens. The well defined morphology and precisely choreographed division of trypanosomatid cells makes morphological analysis a powerful tool for analyzing the effect of mutations, chemical insults and changes between lifecycle stages. High-throughput image analysis of micrographs has the potential to accelerate collection of quantitative...
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