The fatty acid translocase gene CD36 and lingual lipase influence oral sensitivity to fat in obese subjects.

doi:10.1194/jlr.M021873

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Article

The fatty acid translocase gene CD36 and lingual lipase influence oral sensitivity to fat in obese subjects.

Journal of lipid research - 1 Mar 2012

Pepino Marta Yanina, Love-Gregory Latisha, Klein Samuel, Abumrad Nada A

Abstract excerpt

The precise orosensory inputs engaged for dietary lipids detection in humans are unknown. We evaluated whether a common single nucleotide polymorphism (rs1761667) in the CD36 gene that reduces CD36 expression and the addition of orlistat, a lipase inhibitor, to reduce FA release from triacylglycerols (TGs), the main component of dietary fats, would attenuate fat orosensory sensitivity in humans. Twenty-one obese...

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Identifiers

PMID: 22210925
DOI: 10.1194/jlr.M021873
PMCID: PMC3276480

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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