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Article

Clinical and metabolic features of adult-onset diabetes caused by ABCC8 mutations.

Diabetes care - 1 Feb 2012

Riveline Jean-Pierre, Rousseau Elise, Reznik Yves, Fetita Sabrina, Philippe Julien, Dechaume Aurélie, Hartemann Agnès, Polak Michel, Petit Catherine, Charpentier Guillaume, Gautier Jean-François, Froguel Philippe, Vaxillaire Martine

Abstract excerpt

OBJECTIVE: Gain-of-function ABCC8/sulfonylurea (SU) receptor 1 mutations cause neonatal diabetes mellitus (NDM) or late-onset diabetes in adult relatives. Given the effectiveness of SU treatment in ABCC8-NDM patients, we further characterized late-onset ABCC8-associated diabetes. RESEARCH DESIGN AND METHODS: Seven adult subjects from three NDM families and one family with type 2 diabetes were studied. Insulin...

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Share to ATP-Binding Cassette Transporters
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Potassium Channels, Inwardly Rectifying

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Source

Open in PubMed Open full text

Identifiers

PMID: 22210575
DOI: 10.2337/dc11-1469
PMCID: PMC3263906

Genes

ABCC8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Clinical and metabolic features of adult-onset diabetes caused by ABCC8 mutations.PMID 22210575Read ↗

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