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Article

Metabolic variation during development in culture of Leishmania donovani promastigotes.

PLoS neglected tropical diseases - 1 Dec 2011

Silva Ana Marta, Cordeiro-da-Silva Anabela, Coombs Graham H

Abstract excerpt

The genome sequencing of several Leishmania species has provided immense amounts of data and allowed the prediction of the metabolic pathways potentially operating. Subsequent genetic and proteomic studies have identified stage-specific proteins and putative virulence factors but many aspects of the metabolic adaptations of Leishmania remain to be elucidated. In this study, we have used an untargeted metabolomics...

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PMID: 22206037
DOI: 10.1371/journal.pntd.0001451
PMCID: PMC3243725

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