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Article

Protocadherin-12 deficiency leads to modifications in the structure and function of arteries in mice.

Pathologie-biologie - 1 Feb 2012

Philibert C, Bouillot S, Huber P, Faury G

Abstract excerpt

We studied the role of protocadherin-12 on arterial function. This protein belongs to the cadherin superfamily and is located at the intercellular junctions of endothelial cells where it promotes homotypic cellular adhesion. We previously showed that mice deficient for PCDH12 exhibited developmental growth retardation owing to placenta defects without altering neither survival nor fertility. Here, we investigated...

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Source

Identifiers

PMID: 22205043
DOI: 10.1016/j.patbio.2011.11.005

Genes

PCDH12

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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