Article
Pathoanatomy of cerebellar degeneration in spinocerebellar ataxia type 2 (SCA2) and type 3 (SCA3).
Cerebellum (London, England) - 1 Sept 2012
Scherzed W, Brunt E R, Heinsen H, de Vos R A, Seidel K, Bürk K, Schöls L, Auburger G, Del Turco D, Deller T, Korf H W, den Dunnen W F, Rüb U
Abstract excerpt
The cerebellum is one of the well-known targets of the pathological processes underlying spinocerebellar ataxia type 2 (SCA2) and type 3 (SCA3). Despite its pivotal role for the clinical pictures of these polyglutamine ataxias, no pathoanatomical studies of serial tissue sections through the cerebellum have been performed in SCA2 and SCA3 so far. Detailed pathoanatomical data are an important prerequisite for the...
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