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Article

Malignant progression in O6-methylguanine-DNA methyltransferase-deficient esophageal cancer cells is associated with Ezrin protein.

DNA and cell biology - 1 May 2012

Su Yaoyao, Liu Ran, Sheng JingYi, Liu Hui, Wang Yi, Pan Enchun, Guo Wei, Pu Yuepu, Zhang Juan, Liang Geyu, Tang Derong, Yin Lihong

Abstract excerpt

The abnormal function of O(6)-methylguanine-DNA methyltransferase (MGMT) is reported to be associated with the occurrence of various tumors and malignant tumor progression. However, little evidence is available to describe its role in esophageal carcinogenesis. To address this issue, we constructed a stable MGMT-silenced esophageal cancer cell line by RNA interference, and exposed the cells to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22196440
DOI: 10.1089/dna.2011.1318

Genes

MGMT

Provenance

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Related research

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Malignant progression in O6-methylguanine-DNA methyltransferase-deficient esophageal cancer cells is associated with Ezrin protein.PMID 22196440Read ↗

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Abnormal MGMT promoter methylation may contribute to the risk of esophageal cancer: a meta-analysis of cohort studies.Semantic proximity Read ↗

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