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Article

Association between Helicobacter pylori cagA-related genes and clinical outcomes in Colombia and Japan.

BMC gastroenterology - 22 Dec 2011

Watada Masahide, Shiota Seiji, Matsunari Osamu, Suzuki Rumiko, Murakami Kazunari, Fujioka Toshio, Yamaoka Yoshio

Abstract excerpt

BACKGROUND: Specific genotypes of several virulence factors of Helicobacter pylori (eg, cagA-positive, vacA s1, oipA "on" and babA-positive) have been reported to be predictors of severe clinical outcomes. Importantly, the presence of these genotypes correlates with each other. We hypothesized that novel virulence genes correlate with the presence of cagA. Therefore, we aimed to find novel candidate virulence...

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Identifiers

PMID: 22189161
DOI: 10.1186/1471-230X-11-141
PMCID: PMC3260095

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