Article
Analyses of CDC2L1 gene mutations in keloid tissue.
Clinical and experimental dermatology - 1 Apr 2012
Zhang G, Jiang J, Luo S, Tang S, Liang J, Yao P
Abstract excerpt
BACKGROUND: Keloid disease is the result of a deregulated wound-healing process. Loss of heterozygosity on chromosome 1p36 has been shown to be associated with keloid formation in humans. The cell division cycle 2-like 1 (CDC2L1) gene is known to be essential for eukaryotic cell-cycle control, and has also been mapped to 1p36. AIM: To verify the possible association between keloid disease and somatic mutation of...
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