Article
Genetic susceptibility to keloid scarring: SMAD gene SNP frequencies in Afro-Caribbeans.
Experimental dermatology - 1 Jul 2008
Brown Jason J, Ollier William, Arscott Guyan, Ke Xiayi, Lamb Janine, Day Philip, Bayat Ardeshir
Abstract excerpt
Keloid disease (KD) is a fibroproliferative dermal tumour of unknown aetiology. The increased familial clustering in KD, its increased prevalence in certain races and increased concordance in identical twins suggest a strong genetic predisposition to keloid formation. The highest incidence of keloids is found in the black population, where it has been estimated around 4-6% and up to 16% in random samples of black...
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