Article
[Contribution of genetic polymorphism to the formation of individual genome sensitivity in workers engaged in heat and power industry].
Gigiena i sanitariia - 1 Jan 2000
Minina V I, Savchenko Ia A, Bakanova M L, Ostaptseva A V, Popova O S, Shatalina I V, Akin'china L V, Druzhinin V G
Abstract excerpt
The paper presents the results of investigating an association between the frequency of chromosome aberrations and the CYP1A1, CYP1A2*1F GSTM1, and GSTT1 genes involved in xenobiotic biotransformation in workers engaged in heat and power engineering. The group of workers is shown to have a significantly higher rate of metaphases with aberrations (4.03 +/- 0.17%; n = 231) than the control group (2.06 +/- 0.17%; n...
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