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Article

Reduced CD36-dependent tissue sequestration of Plasmodium-infected erythrocytes is detrimental to malaria parasite growth in vivo.

The Journal of experimental medicine - 16 Jan 2012

Fonager Jannik, Pasini Erica M, Braks Joanna A M, Klop Onny, Ramesar Jai, Remarque Edmond J, Vroegrijk Irene O C M, van Duinen Sjoerd G, Thomas Alan W, Khan Shahid M, Mann Matthias, Kocken Clemens H M, Janse Chris J, Franke-Fayard Blandine M D

Abstract excerpt

Adherence of parasite-infected red blood cells (irbc) to the vascular endothelium of organs plays a key role in the pathogenesis of Plasmodium falciparum malaria. The prevailing hypothesis of why irbc adhere and sequester in tissues is that this acts as a mechanism of avoiding spleen-mediated clearance. Irbc of the rodent parasite Plasmodium berghei ANKA sequester in a fashion analogous to P. falciparum by...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22184632
DOI: 10.1084/jem.20110762
PMCID: PMC3260870

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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