Article
<i>In Vivo</i> Function of PTEX88 in Malaria Parasite Sequestration and Virulence
28 Mar 2015
Abstract excerpt
Malaria pathology is linked to remodeling of red blood cells by eukaryotic Plasmodium parasites. Central to host cell refurbishment is the trafficking of parasite-encoded virulence factors through the Plasmodium translocon of exported proteins (PTEX). Much of our understanding of its function is based on experimental work with cultured Plasmodium falciparum, yet direct consequences of PTEX impairment during an...
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