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Article

Oncologic surveillance for subjects with biallelic mismatch repair gene mutations: 10 year follow-up of a kindred.

Pediatric blood & cancer - 1 Oct 2012

Durno Carol A, Aronson Melyssa, Tabori Uri, Malkin David, Gallinger Steven, Chan Helen S L

Abstract excerpt

BACKGROUND: Heterozygous germline mutations in DNA mismatch repair (MMR) genes cause Lynch syndrome. Biallelic MMR mutations cause a distinct syndrome characterized by brain tumors, lymphoid malignancies, and gastrointestinal cancers during childhood. These children usually succumb to multiple ca...

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Source

Identifiers

PMID: 22180144
DOI: 10.1002/pbc.24019

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22180144-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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