Article
A brain region-specific predictive gene map for autism derived by profiling a reference gene set.
PloS one - 1 Jan 2011
Kumar Ajay, Swanwick Catherine Croft, Johnson Nicole, Menashe Idan, Basu Saumyendra N, Bales Michael E, Banerjee-Basu Sharmila
Abstract excerpt
Molecular underpinnings of complex psychiatric disorders such as autism spectrum disorders (ASD) remain largely unresolved. Increasingly, structural variations in discrete chromosomal loci are implicated in ASD, expanding the search space for its disease etiology. We exploited the high genetic heterogeneity of ASD to derive a predictive map of candidate genes by an integrated bioinformatics approach. Using a...
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