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Article

Corticosteroid-associated avascular necrosis: dose relationships and early diagnosis.

Annals of the New York Academy of Sciences - 1 Dec 2011

Aaron Roy K, Voisinet Anne, Racine Jennifer, Ali Yousaf, Feller Edward R

Abstract excerpt

Corticosteroids are the most common etiological factor in nontraumatic avascular necrosis (AVN) of bone, accounting for about 10% of arthroplasties performed annually in the United States. Evidence is conflicting on the relative importance of peak dose, daily dose, or cumulative dose, and most likely all three represent "high dose" corticosteroid administration and play a role in AVN. The etiology may be...

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PMID: 22172038
DOI: 10.1111/j.1749-6632.2011.06218.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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